Explaining microbial population genomics through phage predation
نویسندگان
چکیده
منابع مشابه
Evolutionary consequences of intra-patient phage predation on microbial populations
The impact of phage predation on bacterial pathogens in the context of human disease is not currently appreciated. Here, we show that predatory interactions of a phage with an important environmentally transmitted pathogen, Vibrio cholerae, can modulate the evolutionary trajectory of this pathogen during the natural course of infection within individual patients. We analyzed geographically and ...
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SUMMARY We have developed a software package, Cortex, designed for the analysis of genetic variation by de novo assembly of multiple samples. This allows direct comparison of samples without using a reference genome as intermediate and incorporates discovery and genotyping of single-nucleotide polymorphisms, indels and larger events in a single framework. We introduce pipelines which simplify t...
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ژورنال
عنوان ژورنال: Nature Precedings
سال: 2009
ISSN: 1756-0357
DOI: 10.1038/npre.2009.3489